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US Oak Ridge National Laboratory Restarts Tungsten-188/Rhenium-188 Generator Production to Support Targeted Cancer Therapy Research

US Oak Ridge National Laboratory Restarts Tungsten-188/Rhenium-188 Generator Production to Support Targeted Cancer Therapy Research

The US Department of Energy's Oak Ridge National Laboratory (ORNL) recently restarted and upgraded its tungsten-188/rhenium-188 (W-188/Re-188) generator manufacturing operations to meet the demand for the rare medical isotope rhenium-188 in targeted cancer therapy research. The laboratory last manufactured such generators in 2011. Radiochemist Becca Hores demonstrated the assembly process of the W-188/Re-188 generator. Depending on radioactivity levels, these generators must be assembled in gloveboxes or hot cells. Image credit: Maggie Gregg/Oak Ridge National Laboratory, US Department of Energy. Rhenium-188 is produced by the radioactive decay of tungsten-188. ORNL irradiates tungsten-186 in the High Flux Isotope Reactor (HFIR) to produce tungsten-188...

2026-08-12

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