Russia's MEPhI Electrospray Ionization Triple Quadrupole Mass Spectrometer Listed in Russia's Key Scientific Instrumentation Projects

According to the 2025 activity report recently released by the Russian Ministry of Science and Higher Education, the "triple quadrupole mass spectrometer with electrospray ionization" developed by the National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) has been listed as one of the 8 successful projects under the federal program "Development of Domestic Civil Instrumentation for Scientific Research."

The mass spectrometer, developed under the guidance of MEPhI Professor Alexey Sysoev, is primarily used for quantitative analysis and identification of chemical substances, particularly suitable for identifying relevant components in complex mixtures. Previously, all such instruments on the Russian market were imported. This independently developed chromatography-mass spectrometry system is capable of handling non-volatile compounds and can serve multiple fields including environmental monitoring, pharmaceuticals, and forensic identification. The equipment has passed national testing and is about to enter the Russian market. According to reports, the annual domestic demand for such instruments in Russia exceeds 50 units.

Meanwhile, the MEPhI Mass Spectrometry Laboratory is also advancing the development of another instrument — the quadrupole time-of-flight mass spectrometer. This project was recently approved by the Russian Academy of Sciences and is also among the 8 projects for developing scientific instruments using domestically manufactured components. The device features a combination of two types of analyzers and can be used for structural analysis of organic compounds such as proteins. Protein sequencing can determine the amino acid sequence in proteins, with applications in medicine, pharmacology, agricultural product monitoring, forensic science, and scientific research.